RECENT ADVANCES IN THE DEVELOPMENT OF POLYHERBAL FORMULATIONS FOR THE TREATMENT OF DIABETES MELLITUS

Ayurveda, a traditional system of medicine, offers holistic approaches to managing various diseases, including the use of herbal medicines. Many researchers have focused on the use of different herbs for curing diseases, and they found it more effective when using a combination of multiple herbs. Polyherbal formulations are combinations of extracts from multiple plants and are explored to enhance therapeutic efficacy. Among the various illnesses, diabetes mellitus is a long-term metabolic condition that poses a serious threat to global health. The role of Ayurveda for curing diabetes includes lifestyle modifications, dietary recommendations, and herbal therapies. Polyherbal formulations are based on Ayurvedic principles that aim to address multiple targets for diabetes management. These formulations often comprise a blend of medicinal plant extracts containing diverse phytoconstituents. Polyherbal formulations are found to be more effective for treating diabetes mellitus due to the synergistic effect of herbal combinations and lower adverse effects than other medicinal systems. This article describes the role of the polyherbal formulations that were developed by various researchers in the last decade for the treatment of diabetes mellitus.