The role of Botox in scar treatment: A comprehensive review

Edosa Derartu Shumet 1, *, Mohammed Hanan Ahmed 1 and Jaria Jallow 2

1 Medical health science center of Yangtze university, Hubei, China.
2 Lishui University Nursing science department, Zhejiang, China.
 
Review
International Journal of Science and Research Archive, 2024, 13(02), 1878–1883.
Article DOI: 10.30574/ijsra.2024.13.2.2337
Publication history: 
Received on 20 October 2024; revised on 28 November 2024; accepted on 30 November 2024
 
Abstract: 
Botox is a neurotoxin which is widely used for cosmetic and therapeutic applications. Recently, it has shown promise in the treatment of hypertrophic and keloid scars. This review aims to examine the current literature to assess the efficacy of Botox in managing scars. Its mechanism of action centers on reducing the tension exerted on healing wounds by underlying muscles. This reduction in tension is crucial because excessive muscle movement can disrupt the delicate process of tissue repair, potentially leading to wider, more noticeable, or hypertrophic scars. Other mechanisms include inhibition of fibroblast activity and decreased collagen production. In addition, it reduces the expression of inflammatory markers. In conclusion, Botox is a safe and effective non-invasive treatment for hypertrophic scars, keloids as well as post-surgical scars. However it is ineffective in other types of scars.
 
Keywords: 
Botulinum toxin; Hypertrophic scars; Keloids; Neurotoxin; Surgical wound
 
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Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0