Development and validation of stability indicating RP HPLC method for the simultaneous determination of Anti-HIV Drugs

For the best suppression of HIV infection, the World Health Organization (WHO) suggests using specific combinations of ARV medications. There are various types of antiretroviral medicines that work on various stages of the life cycle of HIV. Highly active antiretroviral therapy (HAART) is the use of several medications that target various viral targets. HAART preserves immune system function, reduces the patient's overall HIV burden, and guards against opportunistic infections, which frequently result in mortality.For the identification of Afatinib-related compounds in pharmaceutical dosage forms, the currently established Stability Indicating RP-UPLC approach was proven to be straightforward, quick, precise, and specific. High sample throughput is made possible by the method's lower chromatographic duration and preparation. We may infer that the current approach can be used for routine analysis of Afatinib-related compounds in pharmaceutical dosage forms based on the results of all validation parameters.