New approaches for management of diabetes mellitus: A review

N. RAJAVEL 1, *, RAHIMA 1, KR. PRIYADHARSHINI 1 and M. FATHIMA BASHEERA 2

1 Doctor of Pharmacy, Department of Pharmacy Practice, Arulmigu Kalasalingam College of Pharmacy, Krishnankoil, Virudhunagar-626126, Tamil Nadu, India.
2 Assistant Professor, Department of Pharmacy practice, Arulmigu Kalasalingam College of Pharmacy, Krishnankoil, Virudhunagar-626126, Tamil Nadu, India.
 
Review
International Journal of Science and Research Archive, 2024, 13(01), 073–079.
Article DOI: 10.30574/ijsra.2024.13.1.1613
Publication history: 
Received on 19 July 2024; revised on 30 August 2024; accepted on 02 September 2024
 
Abstract: 
Diabetes mellitus is a multifaceted, non-communicable endocrine condition marked by persistent hyperglycaemia and related complications that impact multiple organs. The incidence of DM is on the rise, with estimates predicting over 640 million cases worldwide by 2040. This review explores innovative strategies for diabetes management, highlighting advancements in nanotechnology, statin therapies, stem cell treatments, gene therapy, and herbal remedies. Each strategy offers distinct advantages and challenges, ranging from nanotechnology's capability for continuous glucose monitoring and targeted drug delivery to the role of statins in mitigating cardiovascular risks among diabetic patients. Furthermore, stem cell methods and gene therapy present promising prospects for creating insulin-producing cells and providing immunological interventions, while herbal treatments serve as effective adjuncts with minimal side effects. Despite these advancements, a definitive cure for DM remains elusive, emphasizing the necessity for comprehensive management strategies. The review underscores the significance of achieving optimal metabolic control and advocating for public health initiatives that enhance healthcare accessibility and foster patient-centered care. Ultimately, a holistic approach that integrates these emerging technologies and therapies could lead to improved therapy of diabetes and its related complications.
 
Keywords: 
Hyperglycemia; Complications; Glycemic control; Pharmacotherapy
 
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