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Characterization of tuberculosis diagnostics by GeneXpert MTB/Rif in Villa Clara, Cuba
1 Department of Microbiology and Sanitary Chemistry, Laboratory of the Provincial Centre of Hygiene, Epidemiology and Microbiology (CPHEM-VC) of Villa Clara, Cuba.
2 Department of Teaching and Research, Gynaeco-obstetric Hospital "Mariana Grajales" of Villa Clara, Cuba.
3 Parasitology Department. Regional High Specialty Hospital (HARE), Dr. Juan Graham Casasús, México.
4 Department of Veterinary Medicine, Faculty of Agricultural Sciences, Universidad Central "Marta Abreu" de Las Villas, Villa Clara, Cuba.
5 Department of Hygiene and Epidemiology, Faculty of Health Technology and Nursing (FHTN), University of Medical Sciences of Villa Clara (UMS-VC), Cuba.
Research Article
International Journal of Science and Research Archive, 2024, 12(02), 2577–2584.
Article DOI: 10.30574/ijsra.2024.12.2.1537
Publication history:
Received on 10 July 2024; revised on 19 August 2024; accepted on 22 August 2024
Abstract:
GeneXpert MTB/RIF is a real-time polymerase chain reaction molecular test recommended since 2010 that is able to simultaneously detect the presence of Mycobacterium tuberculosis and Rifampicin resistance within two hours. The aim of the research was to characterize the diagnosis of tuberculosis by GeneXpert MTB/RIF in the Provincial Laboratory of Microbiology and Sanitary Chemistry of the Provincial Centre of Hygiene Epidemiology and Microbiology of Villa Clara, Cuba in the period January 2018-December 2020. A descriptive cross-sectional study was conducted. The study population consisted of 710 samples from patients suspected of tuberculosis. Of the total number of samples studied, 131 (18.5%) were positive; Ciego de Avila and Camagüey were the provinces with the highest percentage of positive results, with 53.8% and 32.0%, respectively. Sputum was the predominant sample type with the highest percentage of positivity (20.7%). The group of those previously treated had the highest percentage of positivity (40.0%). It is concluded that the provinces of Ciego de Avila and Camagüey were the provinces with the highest percentages of positivity, and sputum proved to be the most useful sample for GeneXpert MTB/RIF.
Keywords:
GeneXpert MTB/RIF; Positivity; Sputum; Tuberculosis; Villa Clara
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Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
