In vivo immunoloprotective potentials of Plantago lanceolata aqueous extract on methotrexate induced albino male mice

Mohamednoruldin Dh Hazim 1, Ruqaya Mohammed Al-Ezzy 2, * and Ghufran Malek Ealan 1

1 College of Biotechnology, Al-Nahrain University, Baghdad, Iraq.
2 Department of Molecular and Medical biotechnology, College of Biotechnology, Al-Nahrain University, Baghdad, Iraq.
 
Research Article
International Journal of Science and Research Archive, 2021, 03(02), 168–174.
Article DOI: 10.30574/ijsra.2021.3.2.0156
Publication history: 
Received on 04 September 2021; revised on 10 September 2021; accepted on 12 September 2021
 
Abstract: 
This study aimed to evaluate the immunological potential of Plantago lanceolata through determination of (total and absolute count of white blood cell, total count of red blood cell and total count of hemoglobin). The results indicated the ability of plant extract to modulate toxic effect of methotrexate on albino mice by enhancing immunity through all tested parameters All this effect due to the presence of chemical active constituents of plant especially (flavonoid and alkaloids).
 
Keywords: 
Plantago lanceolata; Methotrexate; White blood cells; Water extract; Total account; Differential account and albino male mice
 
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