Validated estimation of Gingerol and Curcumin in multicomponent herbal tablet by UV spectroscopy

Deepak Yadav *, Anagha Raut, Jaya Agnihotri and Sujeet Yadav

H. K. College of pharmacy, Jogeshwari, Mumbai, 400102. India.
 
Research Article
International Journal of Science and Research Archive, 2023, 08(01), 249-253.
Article DOI: 10.30574/ijsra.2023.8.1.0019
Publication history: 
Received on 29 November 2022; revised on 09 January 2022; accepted on 12 January 2023
 
Abstract: 
Ginger, Zingiber officinale Roscoe Family- Zingiberaceae, has been used in Chinese and Indian folk medicine for centuries. Turmeric, Curcuma longa Linn is from the family of Zingiberaceae. There are no reported UV methods for simultaneous estimation of both the extracts, which is necessary in the development of Herbal formulation for these drugs. Hence, a simple UV spectroscopic method was developed and validated for direct estimation of gingerols and curcuminoids assay in pharmaceutical tablet formulations. Methanolic extracts of rhizome extracts were prepared and analyzed at λ max 280 and 421 nm respectively. The developed method was validated for intraday and interday variations as per ICH Q2A guideline and was found to be a stable method. Novel Pharmaceuticals, Nutraceuticals as well as cosmeceutical products can be conveniently analyzed using this method.
 
Keywords: 
Ginger; Turmeric; Multicomponent; UV spectroscopy; Validation
 
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