Treating amyotrophic lateral sclerosis with a bone marrow derived mesenchymal stem cell extracellular vesicles - A case report

Joshua James Crose

doi:10.30574/ijsra.2021.2.2.0058

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Treating amyotrophic lateral sclerosis with a bone marrow derived mesenchymal stem cell extracellular vesicles - A case report

Joshua James Crose ^*

Capitis Medical & Aesthetics, Inc., 1917 Douglas Blvd. Ste. 89, Roseville, Ca. 95661.

Review Article

International Journal of Science and Research Archive, 2021, 02(02), 167–171.

Article DOI: 10.30574/ijsra.2021.2.2.0058

DOI url: https://doi.org/10.30574/ijsra.2021.2.2.0058

Publication history

Received on 27 April 2021; revised on 16 May 2021; accepted on 19 May 2021

Abstract

Amyotrophic Lateral Sclerosis (ALS) is a terminal neurodegenerative disease with only a few minimally effective treatment options. This study treats a patient with Spinal ALS with Bone Marrow Derived Mesenchymal Stem Cell Extracellular Vesicles (BM-MSCEVs) to slow or stop the progress of the disease. After 2 months and 4 treatments, the patient demonstrated improvement in ALS functional scores and most physical exam findings. BM-MSCEVs demonstrate the ability to effectively treat Spinal ALS in this study and open the door for future studies.

Keywords

Mesenchymal Stem Cells; Extracellular Vesicles; Exosomes; Amyotrophic Lateral Sclerosis; ALS; Bone Marrow

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How to cite this article

Joshua James Crose. Treating amyotrophic lateral sclerosis with a bone marrow derived mesenchymal stem cell extracellular vesicles - A case report. International Journal of Science and Research Archive, 2021, 02(02), 167–171. Article DOI: Article DOI: https://doi.org/10.30574/ijsra.2021.2.2.0058

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