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Transition metal (II) complexes with 2- amino methyl benzimidazole derived schiff base: synthesis, characterization and biological activity
Department of chemistry, G. Narayanamma Institute of Technology and Science (Autonomous), Telangana, India.
Research Article
International Journal of Science and Research Archive, 2023, 08(01), 388-392.
Article DOI: 10.30574/ijsra.2023.8.1.0054
Publication history:
Received on 02 December 2022; revised on 20 January 2023; accepted on 22 January 2023
Abstract:
Novel transition metal [Co(ll), Cu(ll), Ni(ll) and VO(ll)] complexes derived from Schiff bases of 2-amino methyl benzimidazole and 2-furan carbaldehyde(BNFM) have been synthesized and characterized by physical, spectral and analytical data. The synthesized Schiff-bases act as tridentate ligand for the complexation reaction with Co (ll),Cu(II), Ni(ll) and VO(ll) ions. The new compounds, possessing the general formula [ML2] where [M=Co (II), Cu (II), Ni(II) and VO(ll)]. The Schiff bases and their complexes have been screened for biological activity against the strains such as Escherichia coli, Staphylococcus aureus, B.Subtilis and Pseudomonas aeruginosa in order to evaluate the effect of complexation of metals with Schiff base. The metal coordinated Schiff bases have shown more antibacterial activity against bacterial species as compared to uncoordinated Schiff-bases.
Keywords:
Schiff bases; Biological activity; 2-amino methyl benzimidazole; Characterization
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
