Toxicological studies of the effects of ethanolic extracts of avocado (Persea Americana Mill.) seed flour on experimental animals

Nwachukwu Chidinma Mabel *, Emerenini Nkechi J, Egege Josephine Nnebuihe and Ogburubi Orieoma

Department of Food Technology Akanu Ibiam Federal Polyteuchnic, Unwana Ebonyi State   Nigeria.
 
Review
International Journal of Science and Research Archive, 2023, 10(02), 946–954.
Article DOI: 10.30574/ijsra.2023.10.2.1016
Publication history: 
Received on 26 October 2023; revised on 13 December 2023; accepted on 16 December 2023
 
Abstract: 
Ethanolic extract of Avocado (Persea americana) seed flour was assessed for histopathologic and haematological parameters of Albino rats treated with varying dosage (250, 500 and 1000mg/kg) of the extracts. The haematological parameters were RBC, PCV, Hb, WBC, PLT, MCV, MCH and MCHC with range of values 7.01 to 7.32x106mm3, 43.40 to 46.80%, 14.86 to 16.12g/dl, 8.94 to 9.26x103mm3, 89.40 to 94.60x103/mm3, 61.93 to 63.97f1, 21.06 to 22.02pg and 33.17 to 34.73g/dl respectively. The seed extracts did not have adverse effects on the hematological parameters. Conclusively, these seeds should be harnessed and utilized for food and feed production.
 
Keywords: 
Ethanolic extracts; Avocado seed; Haematological; Albino rats; Histopathologic
 
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0