Targeted drug delivery via nanoparticles for cancer treatment

Alina Riaz 1, *, Minahil Mansoor 1, Fiza Rehman 2, Kaynat Arif 1 and Zarfeen Fatima 2

1 Department of pharmacy, Health Sciences Wing, The University of Faisalabad, Faisalabad, Pakistan.
2 Department of Biochemistry, Faculty of Science, University of Agriculture, Faisalabad, Pakistan.
 
Review
International Journal of Science and Research Archive, 2024, 13(02), 1777–1796.
Article DOI: 10.30574/ijsra.2024.13.2.2266
Publication history: 
Received on 12 October 2024; revised on 26 November 2024; accepted on 29 November 2024
 
Abstract: 
This review paper addresses the latest techniques for treating cancer as well as the numerous recent studies conducted on nanoparticles as delivery vehicles for anticancer medication. Numerous chemical and structural formulations of nanoparticles have been investigated for their ability to selectively bind to certain targets and to function as a drug delivery system. The surface characteristics and size of nanoparticles are key factors that impact the bio distribution of chemotherapy medications in the body as well as the efficiency of Nano carriers. For targeting cancerous cells and transporting anticarcinogenic drugs in a controlled way, numerous scientific researchers have been led to investigate the usage of magnetic nanoparticles in the cure of oncogenic breast cancer and brain tumor cells. Other drug delivery systems that have been tested include liposomes, magnetic nanoparticles, polymeric micelles, ceramic nanoparticles, and colloidal gold nanoparticles. The application of ceramic nanoparticles in photodynamic therapy for the cure of cancer is also covered in this article. Thus, the article provides a brief overview of the topic with suitable references to review articles and original research articles that describe previous and ongoing research findings related to different types of nanoparticles for drug delivery in cancer treatment.
 
Keywords: 
Targeted drug delivery; Nanoparticles; Cancer nanotechnology; Liposomes; Polymeric nanoparticles; Tumor targeting
 
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