A study to evaluate the effectiveness of topical interventions in two drug combination therapy versus mono drug therapy for the treatment of intravenous cannula related phlebitis of grade 3 or higher that is caused by the use of peripheral intravenous can

Phlebitis—inflammation of the tunica intima of the venous wall—occurred in 13–56% of hospitalized patients 1.   It causes catheter site puss, palpable venous cord, erythema, oedema, and pain. Cannula-related bloodstream infection (CRBSI) complicates phlebitis 2. Phlebitis can cause patient discomfort, a longer hospital stay, and higher medical costs. Topical treatment of phlebitis is highly recommended by the Centre for Disease Control (CDC) & The Infusion Nurses Society (INS) 3 The aim of this study was to examine the efficacy of topical treatment with mono therapy versus Two drug combination therapy.
Methodology: Conducted a hospital-based prospective, observational study. 110 patients were enlisted using a procedure known as sequential sampling. All patients have been assigned to either a group receiving Two drug combination therapy or a group receiving mono therapy by using a lottery system. The Jackson's Visual Infusion Phlebitis 3 (VIP) Scoring System was used to determine the presence and severity of phlebitis. Numerical pain scale was used to identify the pain score.
Result: Phlebitis affected 41% of 50-64-year-olds.62% of patients had mild to moderate pain.75% pain relief and 89% Visual Infusion Phlebitis ( VIP ) score change after the Two drug combination therapy.
Conclusion: The results of the current study support the use of a Two drug combination of drugs for the topical treatment of intravenous cannula-induced phlebitis.