A study on correlation of liver function tests and outcome in patients of dengue

Nitesh Mutyala 1, Mohith Kumar Namagiri 2, Venkat Nag Pratap Reddy Avula 3, Sai Kiran Kondabolu 4, Jayasomeswara Abhinav Maharaj Thota 5, Sai Preethi Athota 6, Yogitha Charishma Kottali 7 and Naga Sampreethi Mokka 8

1 Department of Medicine, Andhra Medical College, Visakhapatnam, India.
2 Department of Medicine, Government College of Medicine, Srikakulam, India.
3 Department of Medicine, Sri Ramachandra Institute of Higher Education and Research, Chennai, India.
4 Department of Medicine, Andhra Medical College, Visakhapatnam, India.
5 Department of Medicine, Andhra Medical College, Visakhapatnam, India.
6 Department of Radiology, Dr Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation, Vijayawada, India.
7 Department of Medicine, Andhra Medical College, Visakhapatnam, India.
8 Department of Medicine, Andhra Medical College, Visakhapatnam, India.
 
Research Article
International Journal of Science and Research Archive, 2024, 13(01), 1200–1205.
Article DOI: 10.30574/ijsra.2024.13.1.1805
Publication history: 
Received on 11 August 2024; revised on 22 September 2024; accepted on 25 September 2024
 
Abstract: 
Dengue, a mosquito-borne viral disease, presents a significant public health threat, particularly in tropical and subtropical regions. This study aims to assess the correlation between elevated serum aminotransferases and dengue severity, focusing on patients at a tertiary care center. The liver is affected to varying degrees in dengue patients, from asymptomatic enzyme elevation to severe hepatitis. The study found that elevated SGOT levels correlate with more severe symptoms, including prolonged fever, abdominal pain, and bleeding manifestations.
 
Keywords: 
Dengue; LFTs; NS1Ag; Aminotransferases
 
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