Review of herbal plant associated with anti-anemic property and mechanism of action

Eric Omo Irinmwinuwa 1, *, Mbah Chikodili Adolphus 2, Raymond Emiakpo Opute 3, Godwin Benard Oyate 4, Juliet Orugbala Chinedu 4, Onyenmechi Johnson Afonne 1 and Prince Chiazor Unekwe 1

1 Nnamdi Azikiwe University Awka, Nnewi Campus, Anambra State, Nigeria.
2 David Umahi University of Health Sciences, Ebonyi State, Nigeria.
3 Madonna College of Health Technology, Nigeria.
4 Ebonyi State College of Nursing Sciences, Uburu, Ebonyi State, Ebonyi, Nigeria.
 
Review
International Journal of Science and Research Archive, 2023, 08(02), 589–601.
Article DOI: 10.30574/ijsra.2023.8.2.2023.0305
Publication history: 
Received on 03 March 2023; revised on 16 April 2023; accepted on 19 April 2023
 
Abstract: 
Anemia is a global public health problem affecting both developing and developed countries, it occurs at all stages of life but is more prevalent in pregnant women and young children. It is one of the commonest associations in patients of heart failure and has been shown to be associated with increased mortality in both acute and chronic heart failure. Conventional drugs (Vitamin B12, Ferrous preparations) used in the management of anemia are either unaffordable or unavailable and may still have undesirable side effects (abdominal discomfort, dry mouth, nausea, constipation). While herbal medicines that are in use are cheap and are thought to be readily available and less toxic. The need for less expensive, and safe management options has stimulated a surge in continuous research towards the use of herbal medicine for the treatment of anaemia. Most of herbal resources used in anaemia management have not been scientifically validated for their claim, and there is paucity of literature on the phytochemial constituents and Mechanism of action. The goal of this review is to expound various plants used for the treatment of anaemia with their phytochemical properties and mechanisms of action in experimental animal models. Twenty one plant with antianaemic activity were thoroughly sought and their findings reviewed. This information will create a center of attention for scientists and consequently play a major role in future research and documentation of herbal resources in the treatment of anaemia. However, Scientists are therefore encouraged to isolate and characterize these medicinal plant.
 
Keywords: 
Herbal plant; Anaemia; Haematology; Phenylhydrazine; Antioxidant
 
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