A prospective study of correlation between microalbuminuria and atherogenic index in evaluating coronary vascular risk in newly diagnosed type 2 diabetes mellitus patients

DEEPESH MAKHIJANI *, GAJENDRA MAHISHALE and BILAL BIN ABDULLAH

Department of General Medicine, Al-Ameen Medical College and Hospital, Vijayapura, Karnataka, India.
 
Research Article
International Journal of Science and Research Archive, 2024, 13(02), 1080–1087.
Article DOI: 10.30574/ijsra.2024.13.2.2241
Publication history: 
Received on 07 October 2024; revised on 14 November 2024; accepted on 17 November 2024
 
Abstract: 
Background: Diabetes mellitus is an important factor associated with increased cardiovascular morbidity and mortality. Today, it is recognized that the presence of microalbuminuria, in addition to being a marker of incipient renal disease in diabetic patients, seems to be also a marker of large vessel disease, and is associated with an increased cardiovascular mortality. AIP-related risk factors and their relationship with vascular plaques in patients with T2DM is also a concern. The possibility of AIP as a predictor along with microalbuminuria and follow-up monitoring of these factors in patients with newly diagnosed type 2 diabetes has to be explored.
Materials and methods: This Prospective Observational study was conducted in the AL AMEEN MEDICAL COLLEGE AND HOSPITAL, VIJAYAPUR. 250 cases of Newly diagnosed type 2 Diabetes Patients from the medicine ward and OPD’s were included in the study excluding the exclusion criteria. Anthropometric measurements were done with blood investigations and Urine Microalbumin examination.
Results: In this study while comparing atherogenic indices and microalbuminuria, positive correlation (®=0.70*) were present and results were found to be highly significant. Mean ±SD of M. albuminuria in group A and group B was 17.944±5.4420 and 81.640±61.7519. Mean ±SD of AIP in group A and group B was 0.4026±0.06527 and 0.6014±0.10584. Results were found to be highly significant.
Conclusion: AIP is an independent risk factor for CVD and in correlation with MAU could predict the occurrence of coronary vascular risk in newly diagnosed T2DM patients. AIP and MAU correlation provides clinicians a reliable basis to identify high-risk patients and formulate treatment strategies
 
Keywords: 
Plasma arteriosclerosis index; Microalbuminuria; Type 2 diabetes; Dyslipidemia
 
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