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Preparation and evaluation of transdermal gel using Naproxen
PRMSS Anuradha College Of Pharmacy, Chikhli, India.
Review
International Journal of Science and Research Archive, 2024, 13(01), 3130–3142.
Article DOI: 10.30574/ijsra.2024.13.1.2003
Publication history:
Received on 10 September 2024; revised on 20 October 2024; accepted on 23 October 2024
Abstract:
The investigation focuses on developing and review of a topical gel that contains the painkiller naproxen a nonsteroidal anti-inflammatory medication nsaid propylene glycol and carbopol were used as penetration enhancers to promote penetrate into the skin and as a gelling agent in the preparation of the gel to guarantee strength physical characteristics such as ph viscosity and appearance were assessed experiments on the releasing of substances within the body using flow-through diffusion cell demonstrated a prolonged release profile and experiments on skin permeation demonstrated efficient absorption tests for stability verified that the gel kept its characteristics under many circumstances the findings imply that this transdermal gel formulation presents a viable substitute for naproxen delivery improving patient compliance by means of non-invasive administration more in vivo research is advised to confirm the therapeutic efficacy and safety of this intervention the investigation focuses on developing and review of a topical gel that contains the painkiller naproxen a nonsteroidal anti-inflammatory medication nsaid propylene glycol and carbopol were used as penetration enhancers to promote penetration into the skin and as a gelling agent in the preparation of the gel to guarantee strength physical characteristics such as ph viscosity and appearance were assessed experiments on the releasing of substances within the body using flow-through diffusion cell demonstrated a prolonged release profile and experiments on skin permeation demonstrated efficient absorption tests for stability verified that the gel kept its characteristics under many circumstances the findings imply that this transdermal gel formulation presents a viable substitute for naproxen delivery improving patient compliance by means of non-invasive administration more in vivo research is advised to confirm the therapeutic efficacy and safety of this intervention
Keywords:
Neproxen; Transdarm Gel; Gel Formulation; Topical analgesic applications; Bioavailability of transdermal gels
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