Liposome: An advanced pharmaceutical carrier in novel drug delivery system

Rani M. Mhetre *, Rupali V. Waghmode, Sandhya S. Khyamgonde, Rohit S. Nilee, Vijaysinh U. Sable and Rahul I. Jadhav

Department of Pharmaceutics, Lokmangal College of Pharmacy, Wadala, Solapur, India.
 
Review
International Journal of Science and Research Archive, 2023, 10(02), 874–894
Article DOI: 10.30574/ijsra.2023.10.2.1049
Publication history: 
Received on 04 November 2023; revised on 10 December 2023; accepted on 13 December 2023
 
Abstract: 
This comprehensive review delves into the dynamic landscape of liposomal drug delivery systems, illuminating their structural intricacies, mechanisms, and multifaceted applications. Beginning with an exploration of the fundamental principles of liposomes, we navigate through their diverse types, encapsulation techniques, and evolving methodologies. The advantages of liposomal drug delivery, from enhanced bioavailability to targeted interventions and reduced side effects, emerge as pivotal themes. The synthesis of experimental and clinical evidence provides a nuanced understanding of challenges and potential innovations, setting the stage for a detailed exploration of liposomes' applications in various therapeutic domains. As we peer into the future, the review unravels the transformative implications of liposomal drug delivery for personalized medicine, chronic disease management, and advancements in cancer therapeutics. The integration of nanotechnology, the advent of smart liposomes, and regulatory considerations add layers to the narrative, offering a holistic perspective on how liposomal drug delivery systems are shaping the future of pharmacy.
 
Keywords: 
Liposomal Drug Delivery System; Nanotechnology Integration; Advancements in Cancer Therapeutics; Liposomes in oncology; Liposomes crossing BBB
 
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