ISSN Approved Journal || eISSN: 2582-8185 || CODEN: IJSRO2 || Impact Factor 8.2 || Google Scholar and CrossRef Indexed
Fast Publication within 48 hours || Low Article Processing Charges || Peer Reviewed and Referred Journal || Free Certificate
Histological study of the mammary gland of lactating albino Wistar rats treated with oil palm sap as galactagogue
1 Department of Human Anatomy, College of Medicine, Faculty of Basic Medical Sciences, Enugu State University of Science and Technology (ESUT) Enugu, Nigeria.
2 Department of Obstetrics and Gynaecology, College of Medicine, Faculty of Clinical Medical Sciences, Enugu State University of Science and Technology (ESUT) Enugu, Nigeria.
Research Article
International Journal of Science and Research Archive, 2024, 11(02), 1816–1823.
Article DOI: 10.30574/ijsra.2024.11.2.0484
Publication history:
Received on 10 February 2024; revised on 17 March 2024; accepted on 20 March 2024
Abstract:
Background: Population of mothers’ resident in Southeastern Nigeria often use the juicy oil palm sap from African (Elaeis guineensis) palm tree commonly called Palm Wine as galactagogue to boost milk production in lactating women. This study investigated the effects of oil palm sap on the histology of mammary gland in lactating rats.
Method: Twenty primiparous female albino wistar rats were used and randomly divided into four groups (n=5, each). The rats in the treated groups received a daily administration of oil palm sap through orogastric method at a dose of 10ml/kg. The positive and negative control groups received 5mg/kg of metoclopramide and 2.5mg/ kg of bromocriptine, respectively while the normal control group received 0.5 ml distilled water. The mammary glands of lactating rats were harvested and fixed with 10% formalin for routine histological procedures and stained with hematoxylin-eosin and viewed under light microscope.
Result: Histological analysis showed that oil palm sap induced the development of the lobuloalveolar system of the mammary glands.
Conclusion: This study scientifically validates the galactagogue properties of oil palm sap and justifies the traditional use of this plant extract to boost milk production in lactating women.
Keywords:
Histology; Mammary gland; Oil palm sap; Metoclopramide; Galactagogue Effect
Full text article in PDF:
Copyright information:
Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
