Formulation and evaluation of herbal cream using ethanolic extract of Emblica officinalis for antibacterial activity

Jitendra Kumar Rai 1, *, Krishanu Samanta 2, Shweta Mishra 1 and Jitendra Jena 2

1 Department of Pharmaceutics, Pharmacy College Azamgarh, Itaura, Chandrshwar, Azamgarh, U.P. India, 276128
2 Department of Pharmaceutical Chemistry, Pharmacy College Azamgarh, Itaura, Chandrshwar, Azamgarh, U.P. India, 276128
 
Research Article
International Journal of Science and Research Archive, 2023, 08(01), 689–694.
Article DOI: 10.30574/ijsra.2023.8.1.0138
Publication history: 
Received on 30 December 2022; revised on 06 February 2023; accepted on 08 February 2023
 
Abstract: 
Skin infections occur commonly and after present therapeutic challenges to practioners due to the growing concerns regarding multidrug resistant bacterial, viral and fungal strain. The aim of present study was to formulate topical cream using Ethanolic leaves extract Emblica officinalis and evaluate In­­- vitro study the antibacterial activity of the ethanolic extracts of dried leaves of Emblica officinalis was determined by using the Agar cup plate method versus different bacteria such as Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa etc. By blending the ethanolic extract of Emblica officinalis (10 % w/w) into aqueous cream we formulated herbal cream. Formulation of herbal cream evaluation their physio-chemical properties, in vitro drug release and in vitro Antibacterial Activity against Staphylococcus aureus, Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa. The herbal cream formulation A5 show better release and effective against bacterial strain
 
Keywords: 
Herbal cream; In-vitro release; Antibacterial activity; Irritancy; Spreadability; Diffusion
 
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