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Exploring the anti-arthritic and anti- inflammatory activity of ethanol extract of Mimosa pudica leaves against complete Freund’s adjuvant (CFA) induced arthritis in Wistar albino rats
1 Department of Pharmacology, Head of the department, Faculty of Pharmacology- Chettinad Academy of Research and Education, Chennai. Tamilnadu, India.
2 Department of Pharmacology, Aadhibhagawan College of Pharmacy. Thiruvannamalai, Tamilnadu, India.
3 Department of Pharmacology, Junior Research Fellow, Siddha Central Research Institute. Chennai, Tamilnadu, India.
Research Article
International Journal of Science and Research Archive, 2024, 13(02), 1918–1929.
Article DOI: 10.30574/ijsra.2024.13.2.2280
Publication history:
Received on 15 October 2024; revised on 26 November 2024; accepted on 29 November 2024
Abstract:
The study explores the potential anti-arthritic and anti-inflammatory effects of an ethanol extract from Mimosa pudica leaves in a rat model of arthritis induced by Complete Freud’s Adjuvant (CFA). The extract’s efficacy was evaluated by measuring key markers associated with inflammation and arthritis. The results revealed a significant reduction in inflammation and arthritis-related symptoms in the treatment group, suggesting the extract's strong anti-inflammatory properties. The findings highlight the therapeutic potential of Mimosa pudicas a natural remedy for arthritis, which could be attributed to its active phytochemicals like flavonoids and alkaloids. Further studies are needed to clarify the underlying mechanisms and explore their possible use in treating human arthritis.
Keywords:
Mimosa pudica; Anti-arthritic activity; Anti-inflammatory effects; Complete Freund’s Adjuvant (CFA); Wistar albino rats; Ethanol extract; Phytochemicals; Flavonoids and alkaloids; Rheumatoid arthritis model
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