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Exploration of anthelmintic potency of Pisonia alba
Department of Pharmacology, SSM College of Pharmacy, Jambai, Bhavani Taluk, Erode District, Tamilnadu-638 312, India.
Research Article
International Journal of Science and Research Archive, 2023, 08(01), 695–700.
Article DOI: 10.30574/ijsra.2023.8.1.0146
Publication history:
Received on 28 December 2022; revised on 06 February 2023; accepted on 09 February 2023
Abstract:
Helminthiasis or worm infestation is one of the most prevalent disease and one of the most serious problems in the world. Pisonia alba (Ceodeus Grandis) plant was selected for exploration of anthelmintic activity because Nyctaginaceae family plants such as Boerhavia diffusa, Bougainvillea glabra, and Mirabilis jalapa L., already tested for the anthelmintic activity and they have potent anthelmintic activity. The Phytochemical test performed in this ethanolic extract of Pisonia alba. This study indicated that the crude ethanol extract produces anthelmintic activity against the Indian earthworm Pheretima Posthuma. Ethanolic extract of Pisonia alba [20, 40, 60 mg/ml] compared with standard drug (Albendazole). The extract showed significant potency when compared with standard drug Albendazole. The plant explored significant anthelmintic activity at 60 mg/ml concentration in time taken for paralyse /death of the earthworms The current investigation indicates the leaves of Pisonia alba have potent anthelmintic activity the further study is needed to explore its full potential.
Keywords:
Pisonia alba; Pheretima posthuma; Anthelmintic activity; Albendazole
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