The effect of intense physical activity session with glutamine supplementation on selected factors of wrestlers' immune system

Sepehri Manesh Mohammad 1, *, Abbasi Moghadam Mahdi 1 and Sohrabi Parisa 2

1 Khorramabad Technical and Vocational College, Khorramabad, Lorestan, Iran.
2 Shahid Rahimi Hospital, Lorestan University of Medical Sciences, Khorramabad, Lorestan, Iran.
 
Research Article
International Journal of Science and Research Archive, 2021, 02(02), 145–150.
Article DOI: 10.30574/ijsra.2021.2.2.0070
Publication history: 
Received on 13 April 2021; revised on 16 May 2021; accepted on 20 May 2021
 
Abstract: 
Athletes with heavy training loads are prone to infectious diseases. It has been shown that these exercises may suppress immune function. The aim of this study was to investigate the effect of one session of intense physical activity with glutamine supplementation on selected factors of wrestlers' immune system. For this purpose, 20 wrestlers were selected and randomly divided into two groups of supplement and placebo. The first blood sample was taken from the subjects. Then they did the Bruce test. Immediately after the end of the test, blood samples were taken from the subjects for the second time and then to the supplement group. The glutamine supplement was given the same amount of maltodextrin per kilogram of body weight and the placebo group. Blood samples were taken from the subjects for the third and fourth time 1 and 2.5 hours after taking the supplement or placebo. After measuring blood factors, the findings were statistically analyzed (ANOVA) at a significance level of p <0.05. The results showed that the percentage of neutrophils in the supplement group increased significantly 2.5 hours after supplementation compared to immediately after exercise and 1 hour after supplementation. This increase was less in the supplement group than in the placebo group. The percentage of lymphocytes in the supplement group decreased significantly 2.5 hours after supplementation compared to the pre-test, immediately after exercise and 1 hour after supplementation, which was less in the supplement group than the placebo group. The percentage of monocytes in the supplement group increased significantly 2.5 hours after supplementation compared to immediately after exercise. This increase was less in the supplement group than in the placebo group. The results of this study showed that glutamine supplementation during strenuous exercise has beneficial effects on the immune system of athletes.
 
Keywords: 
Glutamine; Immune system; Intense physical activity
 
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