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Diabetes mellitus and anti-oxidative stress
1 Biochemistry Department, Azerbaijan Medical University, Azerbaijan.
2 Normal Physiology Department, Azerbaijan Medical University, Azerbaijan.
3 İnternal Medicine Department, Azerbaijan Medical University, Azerbaijan.
Review
International Journal of Science and Research Archive, 2023, 09(01), 390–393.
Article DOI: 10.30574/ijsra.2023.9.1.0425
Publication history:
Received on 20 April 2023; revised on 02 June 2023; accepted on 05 June 2023
Abstract:
The development of diabetes complications, both microvascular and cardiovascular, is significantly influenced by oxidative stress. Diabetes-related metabolic problems lead to an overproduction of mitochondrial superoxide in the heart, small and large vascular endothelial cells, and both. Five key pathways implicated in the pathophysiology of problems are activated as a result of the increased superoxide generation. The purpose of this review is to highlight new insights into the processes through which hyperglycemia produces oxygen free radicals.
Keywords:
Diabetes mellitus; Insulin deficiency; Antioxidative stress; Hyperglycaemia
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
