Diabetes mellitus and anti-oxidative stress

Elshad Abuzar Novruzov; Dilara Magsood Aliyeva; Sabina Anvar Mashadiyeva-Bayramova; Adil Allahyar Bayramov

doi:10.30574/ijsra.2023.9.1.0425

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Diabetes mellitus and anti-oxidative stress

Elshad Abuzar Novruzov ^{1, *}, Dilara Magsood Aliyeva ², Sabina Anvar Mashadiyeva-Bayramova ³, and Adil Allahyar Bayramov ²

1 Biochemistry Department, Azerbaijan Medical University, Azerbaijan.
2 Normal Physiology Department, Azerbaijan Medical University, Azerbaijan.
3 İnternal Medicine Department, Azerbaijan Medical University, Azerbaijan.

Review Article

International Journal of Science and Research Archive, 2023, 09(01), 390–393.

Article DOI: 10.30574/ijsra.2023.9.1.0425

DOI url: https://doi.org/10.30574/ijsra.2023.9.1.0425

Publication history

Received on 20 April 2023; revised on 02 June 2023; accepted on 05 June 2023

Abstract

The development of diabetes complications, both microvascular and cardiovascular, is significantly influenced by oxidative stress. Diabetes-related metabolic problems lead to an overproduction of mitochondrial superoxide in the heart, small and large vascular endothelial cells, and both. Five key pathways implicated in the pathophysiology of problems are activated as a result of the increased superoxide generation. The purpose of this review is to highlight new insights into the processes through which hyperglycemia produces oxygen free radicals.

Keywords

Diabetes mellitus; Insulin deficiency; Antioxidative stress; Hyperglycaemia

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How to cite this article

Elshad Abuzar Novruzov , Dilara Magsood Aliyeva, Sabina Anvar Mashadiyeva-Bayramova and Adil Allahyar Bayramov. Diabetes mellitus and anti-oxidative stress. International Journal of Science and Research Archive, 2023, 09(01), 390–393. Article DOI: https://doi.org/10.30574/ijsra.2023.9.1.0425

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