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Design, synthesis, and spectral characterization of series of thiocarbamides with coumarin backbone
Department of Chemistry, Ghulam Nabi Azad College, Barshitakli, Dist. Akola-444 401 (MS) India.
Research Article
International Journal of Science and Research Archive, 2023, 10(02), 855–859.
Article DOI: 10.30574/ijsra.2023.10.2.1035
Publication history:
Received on 01 November 2023; revised on 10 December 2023; accepted on 12 December 2023
Abstract:
Recently a series of 7-(3-thiocarbamido), 7-(3-phenylthiocarbamido), 7-(3-(1,3-dimethyl) thiocarbamido), 7-(3-methylthiocarbamido), 7-(3-allylthiocarbamido)-4-methyl-2H-chromen-2-one (IIIa-e) had been synthesized by refluxing 7-chloro-4-methyl-2H-chromen-2-one (I) with thiourea, N-phenylthiourea, 1,3-dimethylthiourea, N-methylthiourea and N-allylthiourea (IIa-e) in isopropanol medium in 1:1 molar proportion for 5 hours. All the synthesized compounds structures were justified on the basis of chemical tests, elemental study and spectral characterization.
Keywords:
7-chloro-4-methyl-2H-chromen-2-one; Substituted thioureas; Isopropanol; Sodium Bicarbonate; Ethyl alcohol.
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
