A concise review on breast cancer in pregnancy

Yuvaraj K, Govindhan E, Francis Kevin Raj S, Pavithra J and Muralidharan p *

Department of pharmacology, C.L. Baid Metha College of Pharmacy, Rajiv Gandhi salai, Jyothi Nagar, Thoraipakkam, Chennai-600097, India.
 
Review
International Journal of Science and Research Archive, 2023, 08(02), 475–491.
Article DOI: 10.30574/ijsra.2023.8.2.0272
Publication history: 
Received on 23 February 2023; revised on 01 April 2023; accepted on 04 April 2023
 
Abstract: 
Breast cancer is major serious cancer in the women, it can be easily treated with chemotherapy drugs or by breast conservation surgery if it is diagnosed earlier. However the condition become even worse in those pregnant women, because chemotherapy is the most common first line prophylaxis treatment for breast cancer. In pregnancy diagnosed with breast cancer reveals a complicated chemotherapy because it affect the fetus and eventually produce fetal abnormalities and decreases the survival chances of fetus. The 50% survival chances of breast cancer patient is increased with the early diagnosis. Hormonal factors like estrogen, inheritance of BRCA1 and BRCA2 are the foremost responsible for breast cancer, it can get even worsen due to life style adaptations. Multi-drug resistance is eventually happen due to prolonged chemotherapy.
 
Keywords: 
Breast cancer; BRCA1 and BRCA2; Estrogen; Chemotherapy
 
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0