A comparative study of Serum ALT levels in metabolic syndrome patients with and without NAFLD

Mamta Sagar 1, Sandeep Tripathi 1, * and Rajendra Dhar 2

1 Department of Biochemistry, National Institute of Medical Sciences & Research, Nims University, Jaipur, Rajasthan, India.
2 Department of Medicine, National Institute of Medical Sciences & Research, Nims University, Jaipur, Rajasthan, India. 
 
Research Article
International Journal of Science and Research Archive, 2023, 10(02), 490–496.
Article DOI: 10.30574/ijsra.2023.10.2.0975
Publication history: 
Received on 13 October 2023; revised on 26 November 2023; accepted on 29 November 2023
 
Abstract: 
Background: This study was undertaken to evaluate the Serum ALT levels in Metabolic Syndrome (MetS) patients with and without NAFLD. The objective was to compare the change in serum ALT levels in those patients.
Methods: The study was conducted in the Department of Biochemistry in association with Department of Medicine, National Institute of Medical Sciences and Hospital, Jaipur. At the same time adult diagnosed 150 MetS patients (75 without NAFLD & 75 with NAFLD) were taken. Anthropometric measurements were taken. ALT was measured in serum in both groups. The data obtained was statistically analyzed.
Results: Serum ALT was 67.89 ± 36.26 U/l in MetS with NAFLD while it was 46.03 ± 8.99U/l in without NAFLD.
Conclusions: increased ALT level is highly significant (p value < 0.001) in MetS with NAFLD as compare to without NAFLD. So increase in ALT in blood is associated with NAFLD in MetS patients.
 
Keywords: 
Metabolic Syndrome; NAFLD; SGPT; ALT
 
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