Comparative study of I.V. magnesium sulphate and lignocaine for attenuating the haemodynamic stress during laryngoscopy and intubation

Ram Manohar Reddy P * and Siddartha Patta

Department of Anaesthesiology, NRI Medical College, Guntur A.P, India.
 
Research Article
International Journal of Science and Research Archive, 2023, 08(02), 037–047.
Article DOI: 10.30574/ijsra.2023.8.2.0201
Publication history: 
Received on 18 January 2023; revised on 27 February 2023; accepted on 02 March 2023
 
Abstract: 
Background: Following induction of general anesthesia, laryngoscopy and endotracheal intubation produce pressor response that are somatic visceral reflexes brought on by stimulation of epipharynx and laryngopharynx. To avoid hemodynamic responses to intubation, several strategies have been tested. Agents like opioids, local anesthetics have been used to attenuate such response. Our study was employed with intravenous magnesium sulphate and lignocaine.
Methods: A total of 60 patients of both sexes in the age group between 15-50years, belonging to ASA grade I and II undergoing elective surgery under general anaesthesia. Out of  the 60 patients 30 were randomly included in the L group (lignocaine group) and the other 30 were included in the M group (magnesium sulphate group).
Results: There was fall in heart rate (p < 0.05) noted following induction, laryngoscopy, and intubation, in Magnesium group and Lignocaine group, but the fall in heart rate was more significant in the Magnesium group when compared with the Lignocaine group
Like heart rate there was a significant fall in mean arterial pressure in both the groups, but there was statistically significant fall (p < 0.05) in the Magnesium group when compared with the Lignocaine group.
 
Keywords: 
Magnesium sulphate; Lignocaine; Intubation response; Cardiovascular response
 
Full text article in PDF: 
 
Copyright information: 

Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0