Association of severe autoimmune hypothyroidism with reversible proteinuria: A case report

Salman J. Khan 1, 2, *, Husnain Naveed 3, Muhammad Hashim Khan 4, Shafqat Ullah 5, Calvin Yee Fen Lee 6, Sadaf Alam 7, Fnu Vishal 8 and Seemab Sheikh 9

1 Department of Hematology and Oncology, Mayo Clinic, Jacksonville, Florida, USA.
2 Public Health, University of Massachusetts, Amherst, USA.
3 Shifa College of Medicine, Islamabad, Pakistan.
4 Maimonides Medical Center, New York, USA.
5 Jewish Hospital, Louisville, Kentucky, USA.
6 University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA.
7 Meritus Health General Hospital, Hagerstown, Maryland, USA.
8 Rochester General Hospital, New York, USA.
9 Community Health Center, New Britain, Connecticut, USA.
 
Review
International Journal of Science and Research Archive, 2023, 10(01), 411–413
Article DOI: 10.30574/ijsra.2023.10.1.0766
Publication history: 
Received on 13 August 2023; revised on 19 September 2023; accepted on 22 September 2023
 
Abstract: 
Hypothyroidism is a prevalent medical condition characterized by an underactive thyroid gland, resulting in insufficient thyroid hormone production. This hormone plays an important role in regulating the body's metabolism, so when its levels are low, it can lead to various metabolic disturbances. In this article, we present a case report of a 50-year-old female with severe hypothyroidism who exhibited several symptoms of renal impairment and hypothyroidism. She had proteinuria along with elevated lipid levels. Following a diagnosis of Hashimoto's thyroiditis, the patient was treated with levothyroxine, resulting in a remarkable reversal of her proteinuria and other symptoms. The lipid profile also showed significant improvement without the need for cholesterol-lowering medications. This case report highlights the importance of recognizing and managing thyroid dysfunction in patients with renal abnormalities. It provides valuable insights into the complex interplay between thyroid function, renal abnormalities, and lipid levels.
 
Keywords: 
Hypothyroidism; Proteinuria; Dyslipidemia; Hashimoto’s thyroiditis
 
Full text article in PDF: 
 
Copyright information: 

Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0