Anti-glycation and antioxidant properties of Abutilon indicum plant leaves

Dinesha Ramadas; Santhosh Kumar Nune; Chikkanna D; Maheshwara KV; Vedamurthy Joshi

doi:10.30574/ijsra.2021.2.2.0090

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Anti-glycation and antioxidant properties of Abutilon indicum plant leaves

Dinesha Ramadas ^{1, 5}, Santhosh Kumar Nune ^{2, 3}, Chikkanna D ³, Maheshwara KV ⁴and Vedamurthy Joshi ^{5, *}

1 Adichunchanagiri Institute for Molecular Medicine, Adichunchanagiri Institute for Medical Sciences, Adichunchanagiri University, BG Nagara-571448, Karnataka, India.
2 Department of Medical Biochemistry, Shridevi Institute of Medical Sciences & Research Hospital, Tumakur, Karnataka, India.
3 Department of Medical Biochemistry, Adichunchanagiri Institute for Medical Sciences, Adichunchanagiri University. BG Nagara-571448, Karnataka, India.
4 GIPS, Nijaganahally, KR Nagara Tq, Mysore Dist, Karnataka, India.
5 Department of Pharmaceutics, CORMIL & CMPAT, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara-571 448, Karnataka, India.

Research Article

International Journal of Science and Research Archive, 2021, 02(02), 269-273.

Article DOI: 10.30574/ijsra.2021.2.2.0090

DOI url: https://doi.org/10.30574/ijsra.2021.2.2.0090

Publication history

Received on 29 May 2021; revised on 01 July 2021; accepted on 02 July 2021

Abstract

The study was done to investigate the in vitro anti-diabetic activity of Ethanol-water extract of Abutilon indicum plant leaves. The phytochemicals present in the extract was analyzed by using standard methods. In vitro antioxidant study was done using DPPH radical scavenging activity. The In vitro anti-diabetic studies were done by alpha amylase enzyme, alpha glucosidases enzyme inhibition studies and Glucose uptake in Yeast cells studies. The phytochemical analysis showed that the extract rich with proteins, polyphenols, flavonoids, alkaloids, tannins, polysaccharides. The in vitro antiglycation potential of extract was confirmed through alpha amylase enzyme, alpha glucosidases enzyme inhibition studies and Glucose uptake in Yeast cells studies. The results of the present study showed the significant antioxidant and antidiabetic activity. The potential pharmacological activity of Abutilon indicum might be the presence of phytochemicals.

Keywords

Anti-diabetic; Antioxidant; Abutilon indicum; Phytochemicals

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How to cite this article

Dinesha Ramadas, Santhosh Kumar Nune, Chikkanna D, Maheshwara KV, and Vedamurthy Joshi. Anti-glycation and antioxidant properties of Abutilon indicum plant leaves. International Journal of Science and Research Archive, 2021, 02(02), 269-273. Article DOI: https://doi.org/10.30574/ijsra.2021.2.2.0090

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