Anti-asthmatic activity of Tinospora cordifolia leaves extract against ach and citric acid-induced asthma in rats

Deeparani Urolagin 1, *, Dudekula Sheshbee 2, Ansari Aashif Raza Mohd Imtiyaz 1, Samir Panda 1 and Arundhati Kashyap 1

1 Department of Pharmacology, R R College of Pharmacy, Bangalore, India.
2 Department of Pharmacology, Aditya Bangalore Institute of Pharmacy Education and Research, Bangalore, India.
 
Research Article
International Journal of Science and Research Archive, 2024, 12(01), 586–595.
Article DOI: 10.30574/ijsra.2024.12.1.0829
Publication history: 
Received on 31 March 2024; revised on 08 May 2024; accepted on 11 May 2024
 
Abstract: 
Asthma is one of the common clutters experienced in clinical medication in both grown-ups and children are asthma and it is characterized by irritation of the aviation routes which causes aviation route brokenness. Breathed-in bronchodilators and anti-inflammatory drugs are accessible and compelling and they require long term utilize and are related with side impacts. Typically, why elective and complementary medication is being sort after to anticipate these side impacts. A few restorative plants have anti-inflammatory impact and have demonstrated successful within the treatment of asthma. Citric corrosive, Acetylcholine, Histamine is basically utilized for assessing anti-asthmatic movement of specific sedate. Numerous plants gotten from the normal source play a critical part within the wellbeing care framework. Writing overview on home grown drugs has appeared noteworthy anti-asthmatic movement which has not shown any momentous side impact. The pharmacological component that the phytoconstituents creating the hostile to asthmatic action are not clearly caught on till date. A few herbal formulations have been determined from the Ayurveda, conventional framework of Indian medicine and its extra framework of medication, however to be experimentally approved that they have exhibited pharmacological activity against Asthmatic. As it were less number of logical data of conventional medications is accessible for the treatment of Asthmatic. This survey contains list of restorative plant which have been tried for anti-asthmatic action within the Citric corrosive, Acetylcholine actuated asthmatic in Rodent demonstrate. Rats were divided into 4 groups and given each of them individual intervention based on the activity. Tinospora cordifolia leaf extract shows an anti-asthmatic activity in rats. hence, the data given in this inquiry will offer assistance the analysts for the advancement of elective strategies instead of inhalers and verbal anti-asthmatic drugs for the treatment of asthma and COPD which can minimize the complications.
 
Keywords: 
Anti-asthma; Bronchodilators; Anti-inflammatory; Inhalers; Phytoconstituents
 
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