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ISSN Approved Journal || eISSN: 2582-8185 || CODEN: IJSRO2 || Impact Factor 8.2 || Google Scholar and CrossRef Indexed

Peer Reviewed and Referred Journal || Free Certificate of Publication

Research and review articles are invited for publication in March 2026 (Volume 18, Issue 3) Submit manuscript

A study to assess the knowledge and expected outcome on guidelines directed to medical therapy in heart failure patient undergoing treatment in IP and OP basis at Apollo DRDO hospitals, Hyderabad

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  • A study to assess the knowledge and expected outcome on guidelines directed to medical therapy in heart failure patient undergoing treatment in IP and OP basis at Apollo DRDO hospitals, Hyderabad

Leena C L 1, *, R Sreekanth Reddy 2, G. Nirmala 3, O. Nishitha 4 and D. Maryline Flinsi 5

1 Charge Nurse, Department of Nursing, Apollo DRDO Hospital, Hyderabad, Telangana.

2 Cardiologist, Department of Cardiology, Apollo DRDO Hospital, Hyderabad, Telangana.

3 Chief Nursing Officer, Department of Nursing, Apollo DRDO Hospital, Hyderabad.

4 Charge Nurse, Department of Nursing, Apollo DRDO Hospital, Hyderabad, Telangana, India.

5 Principal, Apollo School of nursing, Indraprastha Apollo hospital, New Delhi, India.

Research Article

International Journal of Science and Research Archive, 2025, 15(02), 472-479

Article DOI: 10.30574/ijsra.2025.15.2.1339

DOI url: https://doi.org/10.30574/ijsra.2025.15.2.1339

Received on 28 March 2025; revised on 05 May 2025; accepted on 08 May 2025

Heart failure is a complex clinical condition. Optimal use of guideline-directed medical therapy (GDMT) can prevent hospitalization and mortality among patients with heart failure (HF). Although the guidelines-directed medical therapy for heart failure patients may incur slightly higher expenses, our primary concern was ensuring patients' adherence to this therapy. By conducting this research, we aimed to determine whether adherence to these guidelines would lead to improved patient outcomes and decreased mortality. The study conducted at Apollo DRDO Hospital in Hyderabad selected 60 patients using the purposive sampling technique. Data was collected with the help of informed knowledge questionnaires with the permission from Nursing Head and Ethical approval from Apollo Hospital Jubilee hills. Patients undergoing treatment for heart failure were administered a knowledge & attitude questionnaire before and after receiving guideline-directed education. Paired t-test analysis revealed a significant improvement in knowledge attitude scores.

The result showed that the mean difference in knowledge scores pre- and post-intervention was 1.93, with a paired t-test value of 10.72 (p < 0.05). This improvement exceeded the critical t-value of ±2.001, indicating a statistically significant enhancement in knowledge. The mean difference in attitude scores pre- and post-intervention was 1.48, with a paired t-test value of 7.75 (p < 0.05), indicating significant improvement in attitude score. And among 60 patients, 6 patients (10%) were readmitted to the hospital and 1 patient (1.67%) died. These findings demonstrate that Guideline-Directed to Medical Therapy (GDMT) is effective in improving outcomes in patients with heart failure and a substantial improvement in quality of life.

Heart Failure; Guideline-Directed Medical Therapy (GDMT); Patient Outcomes; Mortality; Quality Of Life; Evidence-Based Medicine

https://journalijsra.com/sites/default/files/fulltext_pdf/IJSRA-2025-1339.pdf

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Leena C L, R Sreekanth Reddy, G. Nirmala, O. Nishitha and D. Maryline Flinsi. A study to assess the knowledge and expected outcome on guidelines directed to medical therapy in heart failure patient undergoing treatment in IP and OP basis at Apollo DRDO hospitals, Hyderabad. International Journal of Science and Research Archive, 2025, 15(02), 472-479. Article DOI: https://doi.org/10.30574/ijsra.2025.15.2.1339.

Copyright © Author(s). All rights reserved. This article is published under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits use, sharing, adaptation, distribution, and reproduction in any medium or format, as long as appropriate credit is given to the original author(s) and source, a link to the license is provided, and any changes made are indicated.


All statements, opinions, and data contained in this publication are solely those of the individual author(s) and contributor(s). The journal, editors, reviewers, and publisher disclaim any responsibility or liability for the content, including accuracy, completeness, or any consequences arising from its use.

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