A brief review on bioactivity of platinum therapeutics

Subhajit Mukherjee; Koyel Misra; Suparna Paul; Aniruddha Samanta; Sanchita Sarkar

doi:10.30574/ijsra.2024.13.2.2316

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A brief review on bioactivity of platinum therapeutics

Subhajit Mukherjee ^{1, *}, Koyel Misra ¹, Suparna Paul ², Aniruddha Samanta ¹ and Sanchita Sarkar ¹

1 Department of Basic Science, NSHM Institute of Engineering & Technology, NSHM Knowledge Campus Durgapur, West Bengal-713212, India.
2 Department of Chemistry, NTPC Vindhyachal, Singrauli, Madhya Pradesh-486885, India.

Review Article

International Journal of Science and Research Archive, 2024, 13(02), 1664–1672.
Article DOI: 10.30574/ijsra.2024.13.2.2316
DOI url: https://doi.org/10.30574/ijsra.2024.13.2.2316

Publication history

Received on 18 October 2024; revised on 25 November 2024; accepted on 28 November 2024

Abstract

The present review includes a brief introduction over deferent platinum anticancer drugs and their mechanism of action as well as their applications and limitations. Various recently studied Pt(II) complexes are also discussed herein. It also highlights the different possible DNA binding mode for a chemical substance as well as intracellular or extracellular platinum-sulfur interactions.

Keywords

Platinum complexes; Anticancer drugs; Pt-Sulphur adduct; Inorganic metal complexes; DNA binding mechanisms

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How to cite this article

Subhajit Mukherjee, Koyel Misra, Suparna Paul, Aniruddha Samanta and Sanchita Sarkar. A brief review on bioactivity of platinum therapeutics. International Journal of Science and Research Archive, 2024, 13(02), 1664–1672. https://doi.org/10.30574/ijsra.2024.13.2.2316

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