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ISSN Approved Journal || eISSN: 2582-8185 || CODEN: IJSRO2 || Impact Factor 8.2 || Google Scholar and CrossRef Indexed

Peer Reviewed and Referred Journal || Free Certificate of Publication

Research and review articles are invited for publication in March 2026 (Volume 18, Issue 3) Submit manuscript

Exploring the anti-arthritic and anti- inflammatory activity of ethanol extract of Mimosa pudica leaves against complete Freund’s adjuvant (CFA) induced arthritis in Wistar albino rats

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  • Exploring the anti-arthritic and anti- inflammatory activity of ethanol extract of Mimosa pudica leaves against complete Freund’s adjuvant (CFA) induced arthritis in Wistar albino rats

P. Muralidharan 1, *, M. Vignesh 2, P. Madhu maya devi 2, S. Swetha 2, L. Gopi 2 and K. Yuvaraj 3

1 Department of Pharmacology, Head of the department, Faculty of Pharmacology- Chettinad Academy of Research and Education, Chennai. Tamilnadu, India.
2 Department of Pharmacology, Aadhibhagawan College of Pharmacy. Thiruvannamalai, Tamilnadu, India.
3 Department of Pharmacology, Junior Research Fellow, Siddha Central Research Institute. Chennai, Tamilnadu, India.

Research Article
 

International Journal of Science and Research Archive, 2024, 13(02), 1918–1929.
Article DOI: 10.30574/ijsra.2024.13.2.2280
DOI url: https://doi.org/10.30574/ijsra.2024.13.2.2280

Received on 15 October 2024; revised on 26 November 2024; accepted on 29 November 2024

The study explores the potential anti-arthritic and anti-inflammatory effects of an ethanol extract from Mimosa pudica leaves in a rat model of arthritis induced by Complete Freud’s Adjuvant (CFA). The extract’s efficacy was evaluated by measuring key markers associated with inflammation and arthritis. The results revealed a significant reduction in inflammation and arthritis-related symptoms in the treatment group, suggesting the extract's strong anti-inflammatory properties. The findings highlight the therapeutic potential of Mimosa pudicas a natural remedy for arthritis, which could be attributed to its active phytochemicals like flavonoids and alkaloids. Further studies are needed to clarify the underlying mechanisms and explore their possible use in treating human arthritis.

Mimosa pudica; Anti-arthritic activity; Anti-inflammatory effects; Complete Freund’s Adjuvant (CFA); Wistar albino rats; Ethanol extract; Phytochemicals; Flavonoids and alkaloids; Rheumatoid arthritis model

https://ijsra.net/sites/default/files/fulltext_pdf/IJSRA-2024-2280.pdf

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P. Muralidharan, M. Vignesh, P. Madhu maya devi, S. Swetha, L. Gopi and K. Yuvaraj. Exploring the anti-arthritic and anti- inflammatory activity of ethanol extract of Mimosa pudica leaves against complete Freund’s adjuvant (CFA) induced arthritis in Wistar albino rats. International Journal of Science and Research Archive, 2024, 13(02), 1918–1929. https://doi.org/10.30574/ijsra.2024.13.2.2280

Copyright © Author(s). All rights reserved. This article is published under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits use, sharing, adaptation, distribution, and reproduction in any medium or format, as long as appropriate credit is given to the original author(s) and source, a link to the license is provided, and any changes made are indicated.

All statements, opinions, and data contained in this publication are solely those of the individual author(s) and contributor(s). The journal, editors, reviewers, and publisher disclaim any responsibility or liability for the content, including accuracy, completeness, or any consequences arising from its use.

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