A case report on tenofovir induced osteoporosis

Bhavani Dhomakonda; N. MSreeja; Y. Vidhya Reddy; Ankith Reddy; Tadikonda Rama Rao

doi:10.30574/ijsra.2024.11.2.0353

ISSN Approved Journal || eISSN: 2582-8185 || CODEN: IJSRO2 || Impact Factor 8.2 || Google Scholar and CrossRef Indexed

Peer Reviewed and Referred Journal || Free Certificate of Publication

Research and review articles are invited for publication in March 2026 (Volume 18, Issue 3) Submit manuscript

A case report on tenofovir induced osteoporosis

Bhavani Dhomakonda ^{1, *}, N. MSreeja ¹, Y. Vidhya Reddy ¹, Ankith Reddy 1 and Tadikonda Rama Rao ²

1 Department of Pharmacy Practice, CMR College of Pharmacy, Hyderabad, Telangana, India.
2 Principal and Professor, CMR College of Pharmacy, Hyderabad, Telangana, India.

Research Article

International Journal of Science and Research Archive, 2024, 11(02), 183–185.

Article DOI: 10.30574/ijsra.2024.11.2.0353

DOI url: https://doi.org/10.30574/ijsra.2024.11.2.0353

Publication history

Received on 15 January 2024; revised on 25 February 2024; accepted on 27 February 2024

Abstract

The antiretroviral drug tenofovir, is a nucleotide analogue which is used in the treatment of HIV and hepatitis B infections. This drug works by inhibiting the HIV reverse transcriptase enzyme and prevent the synthesis of viral DNA. It is administered as a single 300 mg tablet once daily. This drug is mostly used in the combination with lamivudine, dolutegravir (TLD regimen). Although there has been success in the use of tenofovir in treating HIV infection, there have been some adverse effects associated with it. Multiple studies have implicated tenofovir associated bone loss and renal failure. In order to treat the adverse effects which are caused due to tenofovir, an alternate drug should be administered.

Keywords

Tenofovir; Reverse Transcriptase; TLD regimen; Bone loss

Download Article PDF

https://ijsra.net/sites/default/files/fulltext_pdf/IJSRA-2024-0353.pdf

Preview Article PDF

How to cite this article

Bhavani Dhomakonda, N. MSreeja, Y. Vidhya Reddy, Ankith Reddy and Tadikonda Rama Rao. A case report on tenofovir induced osteoporosis. International Journal of Science and Research Archive, 2024, 11(02), 183–185. Article DOI: https://doi.org/10.30574/ijsra.2024.11.2.0353

Copyright © Author(s). All rights reserved. This article is published under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits use, sharing, adaptation, distribution, and reproduction in any medium or format, as long as appropriate credit is given to the original author(s) and source, a link to the license is provided, and any changes made are indicated.

All statements, opinions, and data contained in this publication are solely those of the individual author(s) and contributor(s). The journal, editors, reviewers, and publisher disclaim any responsibility or liability for the content, including accuracy, completeness, or any consequences arising from its use.