New peptides against B16F10 interfere in cell cycle of melanoma cells

Eric Almeida Xavier * and Fabrício Castro Machado

Experimental Oncology Unit, Department of Microbiology, Immunology and Parasitology, Federal University of São Paulo, São Paulo, SP, Brazil.
 
Review
International Journal of Science and Research Archive, 2024, 11(01), 867–869
Article DOI: 10.30574/ijsra.2024.11.1.0130
Publication history: 
Received on 15 December 2023; revised on 27 January 2024; accepted on 28 January 2024
 
Abstract: 
Peptides have fantastic functions; they can act interfering in various cellular mechanisms such as the cell cycle. Furthermore, because of their high specificity, peptides can be used in antitumor therapy against specific targets. In this work we describe the in vitro action of four antitumor peptide against B16F10 melanoma cells, obtained from immunoglobulin genes. As a result, we show that peptides interfered in the cell cycle of B16F10 cells. In conclusion the present article describes a molecule from immunoglobulin with future potential for in vivo therapeutic test.
 
Keywords: 
Peptide; Antitumor Activity; Cell Cycle; B16F10 Melanoma; Aggressive Tumor Cells
 
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Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0