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ISSN Approved Journal || eISSN: 2582-8185 || CODEN: IJSRO2 || Impact Factor 8.2 || Google Scholar and CrossRef Indexed

Peer Reviewed and Referred Journal || Free Certificate of Publication

Research and review articles are invited for publication in March 2026 (Volume 18, Issue 3) Submit manuscript

Integrating Lifestyle, Dietary and Genetic Factors for Predictive Cardiovascular Risk Reduction

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  • Integrating Lifestyle, Dietary and Genetic Factors for Predictive Cardiovascular Risk Reduction

Shashank Khurana *

Cardiovascular, Former Intern at Grady Memorial Hospital, Lambert High School, Atlanta, Georgia, United States of America.

Research Article

International Journal of Science and Research Archive, 2025, 16(02), 736-743

Article DOI: 10.30574/ijsra.2025.16.2.2351

DOI url: https://doi.org/10.30574/ijsra.2025.16.2.2351

Received on 01 July 2025; revised on 09 August; accepted on 12 August 2025

Heart disease is the number one cause of death in both the United States and worldwide, affecting millions of individuals and their families every year. Despite technological advancements in cardiology and emergency medicine, the global burden of cardiovascular disease continues to increase. However, numerous studies have shown that many cases of heart disease are preventable through modifiable behaviors and early interventions. This paper investigates three major elements contributing to heart disease prevention: physical activity, dietary habits, and genetic predisposition. It provides a comparative analysis of these factors using peer-reviewed literature, government health data, and personal observations made by the author during summer programs at Grady Memorial Hospital and Children’s Healthcare of Atlanta. The evidence strongly supports that although genetics play an important role in determining baseline risk, consistent exercise and proper nutrition can significantly reduce the risk of cardiovascular events, even in genetically predisposed individuals. The paper further emphasizes the importance of health equity, early education, and policy-based interventions to ensure that prevention strategies are accessible to all demographic groups. This research aims to provide a holistic understanding of the interplay between lifestyle and biology in determining heart health and offers strategies that can be applied both individually and systemically to reduce cardiovascular mortality and morbidity.

Cardiovascular Health; Exercise; Diet; Genetics; Preventive Medicine; Heart Disease Risk

https://journalijsra.com/sites/default/files/fulltext_pdf/IJSRA-2025-2351.pdf

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Shashank Khurana. Integrating Lifestyle, Dietary and Genetic Factors for Predictive Cardiovascular Risk Reduction. International Journal of Science and Research Archive, 2025, 16(02), 736-743. Article DOI: https://doi.org/10.30574/ijsra.2025.16.2.2351.

Copyright © Author(s). All rights reserved. This article is published under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits use, sharing, adaptation, distribution, and reproduction in any medium or format, as long as appropriate credit is given to the original author(s) and source, a link to the license is provided, and any changes made are indicated.


All statements, opinions, and data contained in this publication are solely those of the individual author(s) and contributor(s). The journal, editors, reviewers, and publisher disclaim any responsibility or liability for the content, including accuracy, completeness, or any consequences arising from its use.

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