Identifying risk factors for cerebral venous thrombosis in an intensive care unit: Interest in early anticoagulant treatment

Ait Mouheb Tahar 1, *, Amine Zakaria 1, Ait Mokhtar Lynda 1, Ahmed Benyahia Iheb 1 and Labaci Fatima 2

1 Department of anesthesia and resuscitation, Faculty of medicine Algiers, Algeria.
2 Lamine Debaghine Hospital, Bab El Oued, Algeria.
 
Research Article
International Journal of Science and Research Archive, 2024, 11(01), 1506–1510.
Article DOI: 10.30574/ijsra.2024.11.1.0281
Publication history: 
Received on 01 January 2024, revised on 09 Februay 2024, accepted on 12 February 2024
 
Abstract: 
Thrombosis of the dural venous sinus or cerebral veins (CVT) of particular anatomical location of venous thrombosis with a complete or partial occlusion. Treatment of CVT with Heparin followed by VKA is recommended by current guidelines.
Material and methods: We conducted a descriptive cohort study, of CVT recorded at the University Hospital Centre Lamine Debaghine Bab El Oued (Algeria) from April 2020 to December 2023.
Results: We reported 16 cases of cerebral venous thrombosis (CVT) that were admitted to the intensive care ward from April 2020 to December 2023. It represents 7.4% of neurologic deficiency consultation in the emergency department in the studied period. The mean age of our population is 37.38. we found a preponderance in the female population. The aim of our study is to highlight the importance of early anticoagulation.
Discussion: We found that early administration of anticoagulant therapy within the first 24 hours reduced mortality and outcomes in the study population. Our results were consistent with most studies reported in the literature.
Conclusion: the introduction of the precocial anticoagulation impacts the mortality and outcomes in CVT however, more studies on the exact timing of introduction are required to define the right timing.
 
Keywords: 
Cerebral venous sinus thrombosis; Heparin; Venous thrombosis; Cerebral venous sinus thrombosis
 
Full text article in PDF: