Anticancer effects of herbal medicine compounds and novel formulations: A literature review

Cancer remains a global health challenge, necessitating continuous exploration of novel therapeutic strategies. Herbal medicine compounds have garnered significant attention due to their potential anticancer effects. This review summarizes the current state of research on various herbal compounds and their formulations, highlighting their mechanisms of action and potential applications in cancer treatment. Prominent compounds such as curcumin, green tea extract (EGCG), artemisinin, ginsenosides, vinca alkaloids, and quercetin exhibit promising anticancer properties, demonstrating inhibitory effects on cancer cell growth, induction of apoptosis, and modulation of cellular signaling pathways. Additionally, novel formulations, including nanoparticle-based drug delivery systems, are discussed for their potential to enhance the bioavailability and targeted delivery of herbal compounds. While preclinical studies show encouraging results, the translation of these findings into effective clinical therapies requires further investigation. Moreover, considerations of safety, potential drug interactions, and standardization of herbal preparations are crucial for advancing these compounds toward clinical application. This review underscores the importance of a comprehensive and evidence-based approach, integrating herbal medicine compounds and novel formulations into the evolving landscape of cancer treatment.